The Princeton Section of the American Chemical Society
presents the third annual symposium 

Synthesis on Scale:
Process Chemistry in the Pharmaceutical Industry

Friday, January 15th, 2021
10:00 AM – 3:45 PM EST
Remote via Zoom Program

10:00 – 10:10 AM
Welcome and opening remarks
Prof. Spencer Knapp, Rutgers University Symposium Organizer and 2020 Chair, ACS Princeton Section

10:10 – 11:10 AM
“Peroxides in Process Research: Safety through Understanding”
Greg Beutner, Bristol-Myers Squibb (Introduced by Antonio Ramirez, Bristol-Myers Squibb)

11:10 AM – 12:10
“The Development of a Biocatalytic Route to Daurismo”
Angela Puchlopek-Dermenci, Pfizer (Introduced by Pam Tadross, Merck)

12:10 PM – 12:40
Discussion (Greg, Angela, Antonio, and Pam)

— break —

1:10 – 2:10 PM
”Development of Remdesivir for Ebola”
Lars Heumann, Gilead (Introduced by Matt Kraft, Gilead)

2:10 – 3:10 PM
“Commercialization of the Ceftolozane Generation 2 Manufacturing Process”
Pam Tadross, Merck (Introduced by Angela Puchlopek-Dermenci, Pfizer)

3:10 – 3:40 PM
Discussion (Lars, Pam, Matt, and Angela)

3:40 – 3:45 PM
Closing remarks
Prof. Spencer Knapp

Symposium Organizing Committee

Spencer Knapp, Princeton ACS Section
Mukund Chorghade Princeton ACS Section
David Carrick Princeton ACS Section
Louise Lawter Princeton ACS Section
Jennifer Albaneze-Walker
Pam Tadross BMS Merck
Mark Dresel IT Support

Symposium Sponsors

Joseph Martino
Ruben Savizky
Cecilia Marzabadi
Christie McInnis
Rita K. Upmacis
Mirlanda Biba

The Future of Process Chemistry

“New bond forming processes and novel strategies continue to be discovered at an ever increasing rate due to the ingenuity of chemists worldwide. Process intensification concepts, improvements in process analytical technologies (PAT), high throughput methods, and continuous processing combined with machine learning and artificial intelligence (AI) techniques are creating a new vision and new opportunities for the future.” “The industry is also leading the field in terms of improved sustainability and in the development of the next generation of the green agenda. These are, indeed, exciting times for the process chemist.”

Prof. Steve Ley Cambridge, UK 1 January 2021 (excerpted)