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The Princeton Section of ACS
Virtual Meeting of the Princeton ACS Section
Wednesday, February 9, 2022
6:00 pm via Zoom
“Searching for the LEGOS of Life”
Professor Paul Falkowski
Rutgers University, Department of Earth and Planetary Sciences and Marine and Coastal Sciences
Abstract:The black hole of chemistry is the origin of life. Over the past two centuries, many chemists have attempted to understand how molecules can both become replicative and catalytic, but we have, thus far failed to understand autocatalysis that can lead to a system of reactions far from thermodynamic equilibrium. In this talk I will discuss the distance between applied and theoretical chemistry, and most importantly, what questions each of us asked, and have answered, when we were six years old.
Biography: Paul G. Falkowski is the Bennett Smith Professor in Business and Natural Resources; Distinguished Professor, Department of Earth and Planetary Sciences and Founding Director of Rutgers Energy Institute, Rutgers, The State University of New Jersey.
Professor Paul Falkowski’s scientific interests include evolution of the Earth systems, paleoecology, photosynthesis, biophysics, biogeochemical cycles, and symbiosis. Professor Falkowski earned his B.S. and M.Sc. degrees from the City College of the City University of New York and his Ph.D. from the University of British Columbia.
After a post-doctoral fellowship at the University of Rhode Island, he joined Brookhaven National Laboratory in 1976 as a scientist in the newly formed Oceanographic Sciences Division. He served as head of the division from 1986 to 1991 and deputy chair in the Department of Applied Science from 1991-1995, responsible for the development and oversight of all environmental science programs. In 1996, he was appointed as the Cecil and Ida Green Distinguished Professor at the University of British Columbia. He moved to Rutgers University in 1998.
He received a John Simon Guggenheim Fellowship in 1992; the Huntsman Medal in 1998; the Hutchinson Prize in 2000; the Vernadsky medal from the European Geosciences Union in 2007; the Ecology Institute Prize in 2010; the Albert 1st Medal in 2011; and the Tyler Prize for Environmental Achievement in 2018. In 2001, he was elected a Fellow of the American Geophysical Union; in 2002, he was elected to the American Academy of Arts and Sciences; in 2007, he was elected to the United States National Academy of Sciences; in 2008, he was elected as a Fellow of the American Academy of Microbiology; in 2016, he was elected as section chair for Environmental Sciences and Ecology in the United States National Academy of Sciences.
Registration: Registration for the meeting is required. Prior to the meeting, all who have registered will receive information on how to join the virtual platform. To register go to our website at https://www.princeton-acs.org/events/pacs-meeting
Virtual Meeting of the Princeton ACS Section
Thursday, March 10, 2022
6:00 pm via GoToMeeting
“Using Performance Testing to Understand the Benefits of Flavor Delivery Systems in Food Applications”
Carolyn Crosby, Research Investigator, Performance Insights and Adam Toth, Senior Manager, Delivery and Material Technology
International Flavors and Fragrance (IFF), Research & Development
Abstract: Flavor delivery systems can provide versatility and functionality that may not be available from liquid flavors in food applications. Delivery systems offer several benefits including protecting the flavor from harsh food manufacturing processes, improved flavor shelf stability, cost-in use savings, and overcoming hydrophilicity/hydrophobicity issues in food matrices. Performance testing encompasses multiple factors including analytical chemistry, food application technology, physical chemistry, and sensory science to assess if the delivery system is achieving the targeted functionality. The data can provide specific insights about flavor or matrix ingredients in the current experiment as well as be used to build databases to predict future flavor/delivery system behavior in future food applications.
Biographies:
Carolyn Crosby has been with IFF Research & Development for 22 years. She specializes in the performance, release, and modeling of flavors and flavor molecules in flavor delivery systems and food applications. Carolyn uses a wide range of analytical techniques such as headspace, extraction, particle size analysis and rheology to characterize flavor/matrix interactions in delivery systems and foods during preparation, storage, and consumption. She builds flavor performance models using correlations between the analytical data and consumer sensory information. Carolyn has a B.S. degree in Chemistry from the University of Delaware. She previously worked at FMC Corporation in the Phosphorus Chemicals Division, specializing in food phosphate applications.
Adam Toth has been with IFF Research & Development for 22 years. He specializes in the development, characterization and performance of flavor delivery systems for use in various food applications with expertise in extrusion, homogenization, spray drying, and spray chilling processes. Adam currently leads a research team in creating novel encapsulation systems utilizing principles of food chemistry, colloid chemistry, physical chemistry, polymer chemistry, and controlled release to meet the desired functionality in specific food applications. Adam has B.S. and M.S. degrees in Food Science from Rutgers University. Prior to his employment at IFF R&D, he interned for 4 years at the Nourish (Flavor) Division of IFF Creative & Applications while completing his undergraduate studies.
Registration: Registration for the meeting is required. Prior to the meeting, all who have registered will receive information on how to join the virtual platform. To register go to our website at https://www.princeton-acs.org/events/pacs-march-meeting.
Greetings from the Chair
Lisa Veliath, 2022 PACS Chair
Greetings and Happy New Year to all! Welcome to the start of a new year, with it bringing a chance to reflect, refresh and resolve to embark on a fresh start and strive for new aspirations for the year.
For myself as your newly elected Chair, it is my hope to bring you insightful and interesting events and seminars that revolve around the central theme of chemistry. I am joined by an enthusiastic group of Executive Committee members that endeavor to do the same. I wish to extend a special welcome to newly elected Chair Elect Noah Bissonette. Noah is currently a graduate student at Princeton University’s Chemistry Department under Professor David MacMillan. Also, a warm welcome to Lauren Ancona, our new Member-at-Large, who is currently a Research Investigator at IFF specializing in new material evaluations in Research Perfumery. I also would like to give special thank you’s to out-going Chair Allen Jones, Member-at-Large Cary Supalo, and Past-Chair Spencer Knapp for their respective service during the past year.
As a synthetic chemist specializing in fragrance chemistry here at IFF, I hope to bring you opportunities to hear from speakers in this industry as they reveal the chemistry and science behind the
flavors and fragrances, and how fun, flavorful and sweet-smelling it can be! There are many planned exciting events to come, so stay tuned for upcoming events on our website, newsletter, our Facebook group and our new LinkedIn group: Princeton section, American Chemical Society.
We are still amid the pandemic, but I hope that we will be able to return to in-person meetings again sometime soon. In the interim, we will provide virtual meetings that deliver seminars right to your home, office, or mobile phone! The 3rd annual Synthesis on Scale symposium that was held on January 14th, did just that, bringing speakers and attendees together in a global virtual forum for process chemistry. It was a fantastic event!
One notable event that transpired in late 2021, was the announcement of the recipients of the Nobel Prize in Chemistry. This honor was jointly bestowed on Professor David MacMillan of Princeton University and Benjamin List of the University of Cologne/Max Plank Institute. We congratulate them on this prestigious honor. As an organic chemist, I thank them for their contributions toward asymmetric organocatalysis. Bravo!
Lastly, I encourage the younger people, either undergrad or grad students or those just starting their careers in chemistry to consider getting involved with the ACS, and in particular, the Princeton local section. It can connect you to people in different professions and positions, to give you some inspiration and ideas on where your degree could take you. Volunteering is also a way to connect to like-minded people you wouldn’t normally have in your circles.
Thank you, and I am looking forward to an exciting year!
Third Annual PACS “Synthesis on Scale” Symposium Goes Global!
The Third Annual PACS “Synthesis on Scale Symposium, Process Chemistry in the Pharmaceutical Industry” was held remotely by Zoom on Friday, January 14th.
Prof. Stephen L. Buchwald, MIT, provided this written tribute:
"I am always amazed at the creativity of process chemists in tackling the synthesis of even the most complicated molecules, and deriving efficient, practical methods for their preparation. The added necessity of having to worry about cost, supply chain issues, scale up issues and safety issues that only crop up on scale further complicates their task. Heroically, they always rise to the occasion, delivering kilograms and more of product, and paving the way for commercialization. They are to be applauded for their efforts.” January 7, 2022
Speakers, with their titles and introducers:
Welcome and opening remarks – Prof. Spencer Knapp, Rutgers University
Fabrice Gallou, Novartis
“Sustainability as a Driver for Innovation”; introduced by Jennifer Albaneze-Walker, Bristol-Myers Squibb
Megan Smyth, Almac
“Utilising Technology to Deliver Superior Solutions – A CDMO’s Perspective;” introduced by Scott Wharry, Almac
Candice Joe, Bristol-Myers Squibb
“Development of a Scalable Negishi Cross Coupling Process;” introduced by Eric Simmons, Bristol-Myers Squibb
Matthew Beaver, Amgen
“The Role of Continuous Manufacturing to Advance Amgen’s Synthetic Portfolio;” introduced by Oliver Thiel, Amgen
In addition to the presentations, two informal discussions were held with the speakers and introducers. They and the audience engaged in conversation with each other on topics that included early training in chemistry, career advice, public outreach, interactions with colleagues, and the features of day-to-day engagement in process chemistry.
More than 300 chemists from around the world registered for the symposium, and attendance peaked at 107. Important financial and other support was provided by PACS, BMS, IFF, and the speakers’ companies listed above.
Attendee and speaker feedback has been uniformly positive, although we welcome further comments as a basis for making changes for a possible fourth symposium in 2023.
- Spencer